Glutathione and the Liver

It’s a clear fact that we live in a toxic environment. The foods we eat, the air we breathe, the water we drink, all contain chemicals and toxins. For our bodies, the daunting task of getting rid of all these toxins starts in the liver. The liver is one of the hardest working and important organs in the body.

The liver essentially acts as a washing machine, cleansing the body of many damaging toxins before they can enter the bloodstream. It is also responsible for removing dangerous micro-organisms such as bacteria, fungi, viruses, and parasites from the blood before they have the opportunity to invade critical parts of the body where they can do the most damage.

This is important since many of the toxins in our bodies can actually be produced by the body. Fatty tissues can be stored for years and then release toxins into the body as byproducts of energy conversion during activities like exercise, fasting, or during times of stress. Nutritional deficiencies, which are increasingly prevalent due to poor diets and conventionally-grown foods, can also increase the amount of internally produced toxins.

This is one reason a healthy diet is so important, because it supports optimal liver function while at the same time reducing the amount of toxins your body produces. Of the many jobs the liver performs, detoxification is the liver’s most important. The most essential element used by the liver in this process is glutathione (GSH).

How Glutathione Aids in the Detoxification Process

During detoxification, the liver filters the blood, removing large toxins and unwanted chemicals. The liver filters everything ingested by the body and converts any toxins into water-soluble chemicals that are expelled in urine, bile, or stool. This generally occurs in a two-phase process.

During phase I the liver either completely neutralizes toxins or modifies them into weaker, less harmful toxins. Toxins are reduced to smaller fragments, which can then be more easily neutralized in the next phase.

During phase II more powerful enzymes are produced which continue the detoxification process. GSH is produced during phase I, but released into the body, along with other antioxidants, during phase II. Antioxidants protect cells from oxidative damage caused by free radicals. GSH is by far the most important antioxidant produced by the body for neutralizing free radicals and is a principle component of phase II detoxification.

When a person is exposed to large amounts of toxins for long periods there is an imbalance between the two phases. When this occurs, key nutrients such as GSH levels are depleted. Liver damage and oxidative stress can result when phase II processes, dependent on GSH, fail to occur. It is vital to supply the body with proper nutrients while limiting the amount of free radicals we ingest.

We have so many stressors and toxins around us it is essential that our bodies are armed with a way to combat them. For example, imagine a clean sponge that represents your body and a bowl of pure, clean water that represent the nutrients and vitamins your body needs. If you first submerge the sponge in a bowl of muddy water (toxins) and then extract the “toxin-filled” sponge and place it into a bowl of pure, clean water, how much of the pure, clean water (nutrients) do you think it will be able to absorb? Not much, right? However, if you first thoroughly wring out the muddy water and clean it completely (detoxification through the liver) then submerge it into the clean water, you will obviously get much better results absorbing the nutrients your body needs.

That is the effect glutathione has on our liver and its ability to act as a detoxifier. With glutathione taking a central role in our daily detoxification program our liver has the means to extract the toxins from our cells. They are then more readily available to absorb nutrients and perform necessary functions that promote better health.

A healthy diet, coupled with exercise and supplementation, may be the best thing you can do to help your liver function in the most effective and efficient way possible. MaxGXL® and Max N-Fuze® are both designed to support optimal production of glutathione in the body, which will, in turn, assist the liver and other vital organs to perform at their peak.

1. Koch D., “How to promote phase two liver detoxification.”
2. “Liver Detoxification Phase II Support.”


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